| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6292028 | Experimental Parasitology | 2010 | 9 Pages |
Abstract
The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful infection, yet the relationship between these cellular events and clinical disease remains obscure. This review explores the process of cell invasion from the perspective of cell surface interactions, intracellular signaling, modulation of the host cytoskeleton and endosomal compartment, and the intracellular innate immune response to infection.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Conrad L. Epting, Bria M. Coates, David M. Engman,