Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6292075 | Experimental Parasitology | 2011 | 4 Pages |
Abstract
⺠Trypanosoma evansi is a flagellate protozoan can cause neurological disorders in horses and cattle. ⺠The biological roles of nitric oxide (NO) in physiologic processes are many, such as neurotransmission and immune system. ⺠Excessive production of NO can cause neurotoxicity, as well as neurological signs observed in Trypanosomosis. ⺠The indirect determination of NO can be made by the detection of residues of 3-nitrotyrosine (3-NT). ⺠Infection with T. evansi causes changes in the concentrations of protein 3-NT in the CNS of rats. ⺠The increase of 3-NT may be related to inflammation and control of parasitemia at low levels.
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Authors
Francine C. Paim, Aleksandro S. Da Silva, PatrÃcia Wolkmer, Márcio M. Costa, Cássia B. Da Silva, Carlos B.V. Paim, Mauro S. Oliveira, Luiz F.A. Silva, Carlos F. Mello, Silvia G. Monteiro, Cinthia M.A. Mazzanti, Sonia T.A. Lopes,