| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6292093 | Experimental Parasitology | 2012 | 6 Pages |
Abstract
⺠Leishmanicidal flavonoids are strong inhibitors of arginase. ⺠Quercetin interacts with Mn2+ cofactor and with substrate l-arginine at pH 9.5. ⺠Catechol group of flavonoids donate two hydrogen bonds to Asp141. ⺠Quercetin is a mixed inhibitor whereas quercitrin and isoquercitrin are uncompetitive.
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Authors
Edson Roberto da Silva, Claudia do Carmo Maquiaveli, Prislaine Pupolin Magalhães,