Article ID Journal Published Year Pages File Type
6292184 Experimental Parasitology 2011 4 Pages PDF
Abstract
► Vinyl ester tripeptide proteasome inhibitors display trypanocidal activity. ► Peptidyl vinyl esters inhibit the chymotrypsin-like activity of Trypanosoma brucei proteasome. ► Peptidyl vinyl esters are candidates for rational anti-trypanosomal drug development.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Parasitology
Preview
Trypanocidal activity of peptidyl vinyl ester derivatives selective for inhibition of mammalian proteasome trypsin-like activity
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