| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6292207 | Experimental Parasitology | 2011 | 8 Pages |
Abstract
⺠Enzymes of the decarboxylating arm of the TCA cycle in the L3Teladorsagia circumcincta were examined. ⺠Citrate synthase, aconitase, isocitrate dehydrogenase and α-ketoglutarate dehydrogenase activities were detected in tissue homogenates. ⺠Enzyme Vmax and substrate Kms were calculated. ⺠Only citrate synthase had Km values which were markedly different from values obtained from mammalian species. ⺠In terms of catalytic efficiency, this arm of the TCA cycle is most limited by α-ketoglutarate dehydrogenase activity.
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Authors
D.C. Simcock, L.R. Walker, K.C. Pedley, H.V. Simpson, S. Brown,