| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6292346 | Experimental Parasitology | 2011 | 7 Pages |
Abstract
⺠We identified two secreted Giardia proteins; elongation factor-1 alpha (EF-1α) and arginine deiminase (ADI). ⺠Two genes in the Giardia genome encode EF-1α. Promoter luciferase-fusions showed that both genes are transcribed in trophozoites. ⺠The EF-1α protein localizes to the nuclear region but it re-localizes to the cytoplasm during host-cell interaction. ⺠Recombinant EF-1α is recognized by serum from giardiasis patients.
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Authors
Hanna Skarin, Emma Ringqvist, Ulf Hellman, Staffan G. Svärd,