| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6310627 | Chemosphere | 2013 | 7 Pages |
Abstract
⺠Exposure to TiO2 NPs resulted in pathological changes in brain of mice. ⺠Exposure to TiO2 NPs led to ROS production, peroxidation of lipid, protein and DNA in brain. ⺠Exposure to TiO2 NPs caused the increases of p38, JNK, NF-κB, Nrf-2 and HO-1 expression in brain. ⺠Activation of HO-1 through the p38-Nrf-2 signaling pathway may modulate TiO2 NPs-induced oxidative stress in brain.
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Authors
Yuguan Ze, Lei Zheng, Xiaoyang Zhao, Suxin Gui, Xuezi Sang, Junju Su, Ning Guan, Liyuan Zhu, Lei Sheng, Renping Hu, Jie Cheng, Zhe Cheng, Qingqing Sun, Ling Wang, Fashui Hong,