Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6310713 | Chemosphere | 2013 | 13 Pages |
Abstract
⺠The mode of action of PFOA was assessed using an integrative approach in zebrafish. ⺠PFOA affected mRNA and protein expression, liver energy stores but not reproduction. ⺠Results indicated altered membrane permeability and mitochondrial dysfunction. ⺠PFOA also decreased the mitochondrial electron transport system activity. ⺠Glycogen stores were depleted to compensate for inefficient aerobic respiration.
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Authors
A. Hagenaars, L. Vergauwen, D. Benoot, K. Laukens, D. Knapen,