Article ID Journal Published Year Pages File Type
6311293 Chemosphere 2012 11 Pages PDF
Abstract
► Immunotoxic effects of Cu(I) and Irgarol 1051 were studied in a colonial ascidian. ► Both, commonly present in antifouling paints, induce dose-dependent immunosuppression. ► Cu(I) is more toxic than Irgarol, inhibits phagocytosis and affects Ca2+ homeostasis. ► Both change membrane permeability, induce apoptosis and alter hydrolases activities. ► When co-present they act on different subcellular targets.
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