| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6311416 | Chemosphere | 2013 | 9 Pages |
Abstract
⺠In vitro data's relevance to environmental arsenic exposure in whole fish is discussed. ⺠Mechanism of arsenic induced toxicity is similar to that observed in mammalian cell lines. ⺠This study represents a comprehensive approach, with several assays performed for the first time in PLHC-1 cells. ⺠Arsenic trioxide induced cell death is mediated by elevated production of ROS and mitochondrial damage. ⺠Arsenic trioxide induces both apoptotic and necrotic DNA damage as shown by comet assay.
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Environmental Science
Environmental Chemistry
Authors
Vellaisamy Selvaraj, Mindy Yeager Armistead, Menashi Cohenford, Elizabeth Murray,