The joint effects of sulfonamides and their potentiator on Photobacterium phosphoreum: Differences between the acute and chronic mixture toxicity mechanisms

Article ID	Journal	Published Year	Pages	File Type
6311679	Chemosphere	2012	6 Pages	PDF

Abstract

âº The antagonistic effect between SAs and TMP in acute test. âº The synergistic effect between SAs and TMP in chronic test. âº The different protein receptors of SAs in acute and chronic toxicity. âº The different concentrations of SA-binding-receptor in acute and chronic toxicity.

Keywords

QSARs LUC TMP Trimethoprim dhfr dhps 4-Aminobenzoic acid QSAR Potentiator dihydrofolate reductase Dihydropteroate synthase Quantitative structure activity relationships Mixture toxicity Sulfonamides Sulfonamide luciferase Mechanism PABA Molecular docking