Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6312744 | Environment International | 2016 | 8 Pages |
Abstract
In the comparison employed in this study, an interspecies difference of four in RB using AUC assay was identified between the rat and swine models regarding pharmacokinetic differences, which supported the body weight scaling method recommended by US EPA. Future research should focus on the carcinogenic competency (pharmacodynamics) used in experiment animals and humans.
Related Topics
Life Sciences
Environmental Science
Environmental Chemistry
Authors
Luchun Duan, Ravi Naidu, Yanju Liu, Zhaomin Dong, Megharaj Mallavarapu, Paul Herde, Tim Kuchel, Kirk T. Semple,