| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6313431 | Environment International | 2015 | 16 Pages |
Abstract
We observed that higher prenatal and early postnatal Mn levels measured in dentine of deciduous teeth, a novel biomarker that provides reliable information on the developmental timing of exposures to Mn, were associated with poorer behavioral outcomes in school-age boys and girls and better motor function, memory, and/or cognitive abilities in school-age boys. Additional research is needed to understand the inconsistencies in the neurodevelopmental findings across studies and the degree to which differences may be associated with different Mn exposure pathways and biomarkers.
Keywords
WRAVMADSM-IVCES-DDAPPBDEBASC-2PPVTWISC-IVCADsNEPSY-IICPT-IICHAMACOSAUCattention deficit hyperactivity disorderOrganophosphatestandard deviationgeneralized estimating equationsintelligence quotientADHDPeabody Picture Vocabulary TestneurodevelopmentGEELOD یا Limit of detectionHomestandard errorTeethDialkyl phosphatePolybrominated diphenyl etherDiagnostic and Statistical Manual of Mental Disorders, 4th editionconfidence intervallimit of detectionCenter for the Health Assessment of Mothers and Children of SalinasCenter for Epidemiologic Studies Depression ScaleHome observation for measurement of the environmentarea under the curveManganeseGeometric meanCaliforniaChildren
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Authors
Ana M. Mora, Manish Arora, Kim G. Harley, Katherine Kogut, Kimberly Parra, David Hernández-Bonilla, Robert B. Gunier, Asa Bradman, Donald R. Smith, Brenda Eskenazi,