Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6333903 | Science of The Total Environment | 2012 | 8 Pages |
Abstract
⺠CFA consists of spherical crystalline nanoparticles in size range of 11-25 nm. ⺠Alkaline unwinding assay revealed single-strandedness in CFA treated ctDNA. ⺠CFA nanoparticles exhibited the ability to induce ROS and oxidative DNA damage. ⺠Comet and CBMN assays revealed DNA and chromosomal breakage in PBMN cells. ⺠CFA-NPs resulted in mitochondrial membrane damage in PBMN cells.
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Authors
Sourabh Dwivedi, Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Al-Yousef Sulaiman Ali, Javed Musarrat,