Blood pressure in relation to contamination by polychlorobiphenyls and organochlorine pesticides: Results from a population-based study in the Canary Islands (Spain)

Although it has been postulated that background POPs exposure may play a relevant role on elevated BP, we did not observed increased hypertension risk in relation to serum POPs in this cross-sectional study. Conversely, the cyclodiene pesticide aldrin was negatively associated with hypertension, suggesting that cyclodienes could exert an effect opposite of the DDT metabolites. These findings agree with other previous works indicating that POPs may induce divergent actions on BP and suggest that the direction of the association between BP and POPs could be dependent on the chemical structure as well as concentration of the evaluated POP. Prospective studies are needed to clarify the effect exerted by POPs on BP.