Biomarkers responses in muscle of Senegal sole (Solea senegalensis) from a heavy metals and PAHs polluted estuary

► This work studies the relationships between pollutants and energetic metabolism enzymes in Senegal sole. ► Results do not demonstrate biomarkers studied in sole as sensitive tools to measure PAHs exposure. ► AChE, IDH and LDH activity in muscle can be considered a good heavy metal pollution biomarker in sole. ► AChE and IDH were the most sensitive heavy metals pollution biomarkers. ► Results could be very useful for defining pollution control policies and conservation strategies.