Toxicological studies of Irgarol-1051 and its effects on fatty acid composition of Asian sea-bass, Lates calcarifer

This paper explains the toxicological responses of Asian seabass, Lates Calcarifer,upon exposure to different concentrations of Irgarol in laboratory. The 96 h-LC50's of Irgarol for acute exposure was found to be 0.535 ±  0.065 mg/L. Sublethal exposure, 21 days, was done using 50%, 30% and 10% of LC50 value. Further on liver was taken for fatty acid composition study. Results of fresh and control samples were not significantly different (P>0.05) but dominated by Polyunsaturated Fatty Acids (PUFA), followed by Saturated Fatty Acids (SAFA) and Monounsaturated Fatty Acids (MUFA). The trends for other tested groups were significantly different (P<0.05), with species suffered even at a low level of exposure. Results might reveal that Irgarol is toxic and may affect the marine organisms.