Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
637379 | Journal of Membrane Science | 2009 | 6 Pages |
Abstract
In the present work, we show for the first time, that NÉ-carboxymethyllysine is the major product of the in vitro non-enzymatic glycation reaction between fibrillar collagen and glucuronic acid. Dual diffusion membrane system was effectively used for oriented crystal growth of octacalcium phosphate/hydroxyapatite on the biomimetically carboxymethylated collagen fibrils. We hypothesize that the function of biomimetically carboxymethylated collagen is to increase the local concentration of corresponding ions in such a way that a critical nucleus of ions can be formed, leading to the formation of the mineral under specific micro-environment conditions achieved by using diffusion membrane system.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Filtration and Separation
Authors
Hermann Ehrlich, Thomas Hanke, René Born, Christiane Fischer, Andrej Frolov, Tobias Langrock, Ralf Hoffmann, Uwe Schwarzenbolz, Thomas Henle, Paul Simon, Dorin Geiger, Vasily V. Bazhenov, Hartmut Worch,