Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
644367 | Separation and Purification Technology | 2006 | 4 Pages |
Abstract
High-speed counter-current chromatography (HSCCC) was successfully applied to purify ferulic acid from the extracts of Radix Angelicae sinensis, which were extracted by microwave-assisted extraction (MAE). A solvent system consisted of n-hexane–ethyl acetate–methanol–water (3:7:5:5, v/v) was employed. The purity of ferulic acid was over 98% assayed by HPLC. The optimal extraction conditions can be concluded: 850 W of microwave power, 9 min of irradiation time, 90% of ethanol concentration, 6:1 ratio of liquid/solid, 140 min of herbal material soak time and particle sample size 250 ± 9.9 μm, the results showed that microwave-assisted extraction was a promising method for extracting ferulic acid.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Filtration and Separation
Authors
Zhilan Liu, Juan Wang, Pingniang Shen, Chengyun Wang, Yongjia Shen,