| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6468796 | Comptes Rendus Chimie | 2017 | 8 Pages |
Abstract
Deprotonation of a chiral alpha-oxygenated nitrile with the base 2,2,6,6-tetramethylpiperidylmagnesium chloride, TMPMgCl, gives rise to a chiral magnesiated nitrile, and this anion has sufficient configurational stability at low temperature to allow the formation of highly enantiomerically enriched substituted nitrile products after electrophilic quench.
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Madeha R. Alshawish, Graeme Barker, Nicholas D. Measom, Iain Coldham,