Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6468890 | Comptes Rendus Chimie | 2017 | 8 Pages |
Abstract
An efficient nucleophilic allylic substitution of a variety of Morita-Baylis-Hillman adducts with enamines catalyzed by Pd(OAc)2 in the presence of ZnBr2 as a promoter is described in the present study. The reaction gives SN2-type 1,5-dicarbonyl compounds that may subsequently undergo an intramolecular conjugate addition onto the enone moiety affording the corresponding 1,4-adducts. All the synthesized compounds have been isolated in moderate to good yields and fully characterized.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Ghalia Bouhalleb, Jalloul Bouajila, Farhat Rezgui,