A novel electrochemical sensor based on FeS anchored reduced graphene oxide nanosheets for simultaneous determination of dopamine and acetaminophen

•FeS/rGO nanosheets are synthesized via a facile approach for the first time.•FeS/rGO sensor is firstly developed for the measurement of DA and AC.•FeS/rGO sensor exhibits superior electrocatalytic activity and long time stability.•The enhanced performance mainly results from its robust sheet-anchored structure.

In this paper, FeS nanoparticles anchored on reduced graphene oxide (rGO) nanosheets are synthesized via a facile direct-precipitation method. For the first time, a novel electrochemical sensor is developed based on FeS/rGO nanosheets modified glassy carbon electrode (GCE). It has been proved that the resultant FeS/rGO/GCE sensor is very suitable for the individual and simultaneous measurement of dopamine (DA) and acetaminophen (AC) and delivers excellent anti-interference ability to ascorbic acid (AA) and uric acid (UA). Under optimum conditions with differential pulse voltammetry method, a broad linear response versus the concentrations of DA and AC has been observed in the ranges of 2.0 to 250.0 μM and 5.0 to 300.0 μM, respectively. The detection limits for DA and AC are 0.098 μM and 0.18 μM, respectively. Furthermore, the as-obtained sensor has been successfully utilized in real samples and satisfactory results have been achieved. Consequently, by virtue of its outstanding electrocatalytic activity, excellent sensitivity, and long time stability, the as-obtained FeS/rGO modified electrode can be considered as a new promising DA and AC sensor.