Synthesis and characterization of new 1-(α-aminoalkyl)-2-naphthols using pyrazine-1,4-diium trinitromethanide {[1,4-DHPyrazine][C(NO2)3]2} as a novel nano-structured molten salt and catalyst in compared with Ag–TiO2 nano composite

•Synthesis of 1-(α-aminoalkyl)-2-naphthols derivatives as a new Betti bases catalyzed by {[1,4-DHPyrazine][C(NO2)3]2} and Ag–TiO2 nano composite.•Pyrazine-1,4-diium trinitromethanide {[1,4-DHPyrazine][C(NO2)3]2} as a green and novel nano structure molten salt catalyst.•This method has the ability to tolerate a wide variety of substitutions.•This reaction required lower catalytic amount.•This method has the high yield, the shorter reaction times, and compliance with the green chemistry protocols.•Easy recovery and reusability of nanostructure molten salt catalyst.

Pyrazine-1,4-diium trinitromethanide {[1,4-DHPyrazine][C(NO2)3]2} as a green and novel nano-structured molten salt catalyzed the synthesis of new 1-(α-aminoalkyl)-2-naphthol derivatives via the one-pot three-component condensation reaction between 2 or 4-aminopyridine, aromatic aldehydes and β-naphthol at room temperature under solvent-free conditions in comparison with Ag–TiO2 nano composite. Some advantages of the offered method are excellent cost effectiveness, catalytic efficiency, recycle and reusability of the catalyst. Pyrazine-1,4-diium trinitromethanide {[1,4-DHPyrazine][C(NO2)3]2} was fully characterized by IR, 1H NMR, 13C NMR, mass, thermal gravimetry (TG), derivative thermal gravimetry (DTG), differential thermal (DTA), X-ray diffraction patterns (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analysis.

Graphical abstractSynthesis and characterization of new 1-(α-aminoalkyl)-2-naphthols using pyrazine-1,4-diium trinitromethanide {[1,4-DHPyrazine][C(NO2)3]2} as a novel nano-structured molten salt and catalyst in compared with Ag–TiO2 nano composite.Figure optionsDownload full-size imageDownload high-quality image (186 K)Download as PowerPoint slide