Carboxylative Suzuki coupling reactions of benzyl chlorides with allyl pinacolborate catalyzed by palladium nanoparticles

A novel palladium nanoparticles-based catalyst system for carboxylative Suzuki coupling reactions of benzyl chlorides with allyl pinacolborate was developed under mild reaction conditions (low CO2 pressure and temperature) in the absence of any extra ligands. The catalytic system is generated in situ and can thus avoid cumbersome processes for the preparation of metal nanoparticles.