| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 65105 | Journal of Molecular Catalysis A: Chemical | 2014 | 7 Pages |
•The first report on mechanosynthesis route for N-formylation of amines using HIL.•Cationic part of the catalyst is derived from biocompatible material for the first time.•The methodology provides cleaner conversion over shorter reaction time.•The catalyst exhibits high chemoselectivity and high turnover frequency (TOF).•Combination of heterogeneous catalyst and grinding makes the protocol more convenient.
A novel heteropolyanion-based sulfated ionic liquid (HIL-[Ch-OSO3H]3W12PO40) was prepared by pairing sulfate functionalized cholinium cation [N,N,N-trimethyl-2-(sulfooxy)ethanaminium] with catalytically active phosphotungstic acid anion (W12PO403−). It was characterized by 1H NMR, FT-IR, EDX, XRD, TGA and elemental analysis. Catalytic activity of thus prepared HIL was studied in N-formylation of amines under solvent-free grinding condition. The methodology provided cleaner conversion over shorter reaction time with high turnover frequency (TOF) and chemoselectivity.
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