Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
65151 | Journal of Molecular Catalysis A: Chemical | 2014 | 8 Pages |
•Poly(styrene-co-maleic anhydride) was reacted with 4-aminopyridine and used as a polymeric support.•This support was reacted with chlorosulfonic acid for the preparation of solid acid catalyst.•A facile methodology for the solvent-free multicomponent reactions for the synthesis of 4H-Pyrimido[2,1-b]benzothiazole derivatives, tetrasubstituted imidazoles and benzoxanthenones were successfully reported.•This catalyst can promote the yields and reaction times and at least, can be loaded without pre-activation and reused over several repeated runs.
A new N-sulfonic acid based on the polymer-support as a solid acid catalyst is prepared by the reaction of the modified poly(styrene-alt-maleic anhydride) with neat chlorosulfonic acid. 4H-Pyrimido[2,1-b]benzothiazole derivatives, tetrasubstituted imidazoles and benzoxanthenones as selected solvent-free multicomponent reactions were successfully synthesized using this catalyst. These eco-friendly protocols offer several advantages such as green and cost-effective procedures with excellent yield, shorter reaction time, simpler work-up, recovery, and reusability of metal-free solid acid heterogeneous catalyst along with tolerance of a wide range of functional groups.
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