Numerical simulation of fluid–structure interaction in stenotic arteries considering two layer nonlinear anisotropic structural model

The unsteady non-Newtonian blood flow in symmetric stenotic arteries is numerically simulated considering fluid–structure interaction (FSI) using the code ADINA. A two layer hyperelastic anisotropic structural model is used for the compliant arterial wall. The pressure used as outlet boundary condition was obtained running a CFD simulation for each stenosis with a physiologically-realistic time variation of pressure at inlet for different velocities. The obtained pressure drop increases in potential form with the inlet velocity for a fixed stenosis severity. The FSI results show that the maxima velocity and WSS at throat increase in exponential form with stenosis severity. The minimum and maximum effective stress at throat for stenosis severity of S = 70% ranged between 47 kPa and 96 kPa at diastole and systole, respectively.