Article ID Journal Published Year Pages File Type
654905 International Communications in Heat and Mass Transfer 2006 7 Pages PDF
Abstract

The minimum principal of Pontryagin is used solve an optimal control problem for heating a layer of tissue in order to destroy a cancerous tumor. Distributions of temperature and thermal dose in the tissue at different moments of time are computed numerically. The influence of the cool-off period on thermal dose accumulation is investigated.

Related Topics
Physical Sciences and Engineering Chemical Engineering Fluid Flow and Transfer Processes
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