Efficient synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones in the presence of nanocomposites under microwave irradiation

•Omitting any organic solvent and using green chemistry.•The catalysts are recyclable, efficient and easy to separate.•The green and neat approach, easiness and variability in derivatives.

The preparation of quinazolinones has been developed by the condensation of aromatic aldehydes and 2-aminobenzamide in the presence of transition metal-CNTs nanocomposites as novel and recyclable catalyst under microwave and solvent-free conditions. This methodology provides a high speed path for the green and mild synthesis of 2-aryl-2,3-dihydroquinazolin-4(1H)-ones with high structural diversity. The present methodology has advantages such as high activity and reusability of catalysts, heterogeneous nature of catalysts, no use of hazardous organic solvents and green conditions.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (89 K)Download as PowerPoint slide