| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6551955 | Forensic Science International | 2015 | 7 Pages |
Abstract
A fast, specific and robust method for the detection and quantification of JWH-073, JWH-073 N-butanoic acid, and JWH-073 N-(4-hydroxybutyl) in blood and urine has been developed that uses solid-phase extraction (SPE) followed by UPLC-MS/MS analysis. This method has been validated in terms of its linearity (0.1-50Â ng/mL), selectivity, intra-assay and inter-assay accuracy and precision (CVÂ <Â 10%), recovery (75-95%), limits of detection (LODs) (0.08-0.13Â ng/mL), and limits of quantification (LOQs) (0.11-0.17Â ng/mL). Matrix effects, stability, and process efficiency parameters of this method have also been assessed. This method was applied to 2596 authentic samples received by the Department of Toxicology (Istanbul) in the Presidency of Council of Forensic Medicine (Turkey) between September 1, 2012, and February 28, 2015.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Serkan Ozturk, Yeter Erol Ozturk, Oya Yeter, Buket Alpertunga,