Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6553312 | Forensic Science International: Genetics | 2018 | 7 Pages |
Abstract
Based on our results, the number of shared chromosomal segments in collateral relationships was larger than that in lineal relationships with both the second-degree and third-degree kinships. This was probably caused by differences involving chromosomal transitions and recombination between relationships. As we probabilistically evaluated the relationships between simulated pairs based on the number of shared segments using logistic regression, we could determine accurate relationships in >90% of second-degree relatives and >70% of third-degree relatives, using a probability criterion for the relationship â¥0.9. Furthermore, we could judge the true relationships of actual sample pairs from volunteers, as well as simulated data. Therefore, this method can be useful for discerning relationships between two individuals with the same degree of kinship.
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Authors
Chie Morimoto, Sho Manabe, Shuntaro Fujimoto, Yuya Hamano, Keiji Tamaki,