Genetic diversity of 23 autosomal STR loci in a Tibetan population

The genetic polymorphisms of 23 autosomal short tandem repeat (STR) loci included in the Huaxia Platinum System were evaluated in 200 unrelated healthy individuals of Chinese Tibetan population living in the Tibet Autonomous Region. All of the loci reached the Hardy-Weinberg equilibrium. Totally 233 alleles were observed with corresponding allelic frequencies ranging from 0.0025 to 0.5900 and forensic statistical parameters was calculated. The total discrimination power and combined probability of exclusion of the 23 STR loci were over 0.99999999999999999999999999 and 0.999999999, respectively. Results suggested that the 23 STR loci had a relatively high genetic variation, which was suitable for forensic personal identification and paternity testing in Tibetan population.