| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 65741 | Journal of Molecular Catalysis A: Chemical | 2013 | 5 Pages |
•The imidazole-tagged BINAP ligands were synthesized.•Highly enantioselective Ru-catalyzed hydrogenation of β-keto esters in IL/MeOH.•Can effectively reduce Ru leaching and improve catalysts stability.•No significant loss of activity and enantioselectivity after several cycles.
The imidazole-tagged BINAP ligands were synthesized and used for Ru-catalyzed asymmetric hydrogenation of β-keto esters in ionic liquid (IL) systems. The Ru-BINAP catalysts with the imidazolium tags show high catalytic activity and enantioselectivity, which closely parallel the performance of unmodified BINAP. The catalyst recycling experiments using [bmim]Tf2N/MeOH system demonstrated that introducing imidazolium moieties to the BINAP backbone can effectively enhance the affinity of the Ru-catalysts to the IL, reduce Ru leaching and improve catalysts stability, and after several cycles no significant loss of activity and enantioselectivity was observed.
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