| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6592642 | Chemical Engineering Science | 2012 | 6 Pages |
Abstract
⺠Phase transformation mechanism of salt to its free base is studied. ⺠Classical Nucleation Theory is used to interpret the nucleation of the free base. ⺠Phase transformation in excipients suspensions is predicted. ⺠Results are significant for optimal excipients selection. ⺠And thus significant for robust formulation design of solid dosage pharmaceuticals.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
H. Qu, M. Savolainen, L.P. Christensen, J. Rantanen,