| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6592698 | Chemical Engineering Science | 2012 | 11 Pages |
Abstract
⺠In this work nanospheres and nanocapsules for pharmaceutical applications are investigated. ⺠Nanoparticles are produced through solvent displacement in different micromixers. ⺠A preformed PEGylated derivative of cyanoacrylate is used in the experiments. ⺠Results show different mechanisms of formation for nanospheres and nanocapsules. ⺠Experiments are used to derive design and scale-up criteria.
Keywords
DLSRESFESEMPCLPaCaConfined Impinging Jets mixerScale-upPrecipitationPharmaceuticalsCFDComputational fluid dynamicsX-ray photoelectron spectroscopyXPSParticulate processesMixingField emission scanning electron microscopyDynamic Light ScatteringPoly(alkylcyanoacrylates)polyethylene glycolPoly-ε-caprolactonePEG
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
I. Valente, E. Celasco, D.L. Marchisio, A.A. Barresi,