Electrochemical oxidation mechanism of ambroxol and its voltammetric determination in the presence of dodecyl sulfate

The possible oxidation mechanism of ambroxol involves that amino group is irreversibly oxidized to produce an active anilino-radical at a higher potential. Then the free radicals dimerize via 'head-to-tail' coupling to yield a dimer 4-amino-diphenylamine derivative. This dimer is reduced and oxidized quasi-reversibly at a lower potential.