β-Cyclodextrin catalyzed oxidation of some α-amino acids with chloramine-T in alkaline medium: Kinetics and mechanistic studies

The kinetics of oxidation of α-amino acids (AAs) by chloramine-T (CAT) using β-cyclodextrin (BCD) as catalyst was studied in aqueous sodium hydroxide medium at 313 K. The kinetics of reactions was fractional-order with respect to [amino acids] and [β-cyclodextrin]. First-order with respect to [chloramine-T] and inverse fractional-order with respect to [OH−] have been found. Effect of ionic strength, added salt and reaction product (PTS) had no effect on reaction rate. The dependence of the reaction rate on temperature was studied and activation parameters were computed from Arrhenius–Eyring plots. The reaction mechanism and the derived rate law are consistent with the observed experimental results.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (57 K)Download as PowerPoint slideHighlights► Oxidation of α-amino acids by chloramine-T (CAT) using (-cyclodextrin (BCD) as catalyst. ► The kinetics of reactions was fractional-order with respect to [amino acids] and [(-cyclodextrin]. ► The dependence of the reaction rate on temperature was studied and activation parameters were computed from Arrhenius–Eyring plots. ► The reaction mechanism and the derived rate law are consistent with the observed experimental results.