Heat of dissociation from Statistical Thermodynamics: Using calorimetric data to estimate gas hydrate parameters

After estimating hydrate parameters for carbon dioxide and methane sI hydrates, we could relate hydrate enthalpy of dissociation to equilibrium conditions for this binary mixture. We found that the empirical law that states that enthalpy of dissociation of mixed hydrates increases with the increase of occupancy of the largest guest in the large cavity was verified only when the water-poor fluid phase is a vapor. This means that fluid phases also have an important role in hydrate enthalpy of dissociation.