Pd-catalyzed oxidation of alkynes

This review surveys the different Pd-catalyzed procedures leading to the oxidation of the CC bonds. The reactivity and selectivity depend on the substitution of the triple bond, 1,2-diarylethynes being the most reactive. The main oxidation product, an 1,2-diketone, an ester or a furan, depends on both the used procedure and the substrate. Plausible mechanisms are, as far as possible, provided.

Graphical abstractThe different Pd-catalyzed procedures leading to the oxidation of the CC bonds are reviewed.Figure optionsDownload full-size imageDownload high-quality image (88 K)Download as PowerPoint slideResearch highlights► This review highlights the Pd-catalyzed procedures leading to the oxidation of CC bonds. ► The procedures are exemplified using 19 equations and 8 tables. ► Plausible mechanisms and reactive intermediates are depicted in 5 schemes.