Optimization of high pressure extraction processes for the separation of raspberry pomace into lipophilic and hydrophilic fractions

- Pressurized liquid and supercritical fluid extraction applied to raspberry pomace.
- Processes optimized by central composite design and response surface methodology.
- Pressure had largest effect on extract yield in supercritical CO2 extraction.
- 2-Step biorefining gave up to 15% lipophilic and to 25% hydrophilic extracts.
- Hydrophilic extracts demonstrated high antioxidant capacity.