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Compaction of chemically defined cell culture media increases its dissolution rate through an increase of solvent accessible surface area

Article ID Journal Published Year Pages File Type
6676100 Powder Technology 2016 8 Pages PDF
Keywords
mAbρtchemically defined mediadpmUPLCFBRMρbppmCDMCCmMonoclonal antibodyDissolutionFocused beam reflectance measurementChoBiotechnologyChinese Hamster Ovarytapped densitybulk densityCell culture mediaSolvent accessible surface areaFTIRFourier transformed infrared spectroscopyparts per millionUltra High Performance Liquid ChromatographyGranules
Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
Preview
Compaction of chemically defined cell culture media increases its dissolution rate through an increase of solvent accessible surface area
Authors
Andrew Salazar, Julia Bleifuß, Anke Simon, Sabrina Schüßler, Michael Keusgen, Nikolai Stankiewicz, Jörg von Hagen,
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Journal
Powder Technology
Journal: Powder Technology
Related Categories
mAb
ρt
chemically defined media
dpm
UPLC
FBRM
ρb
ppm
CDM
CCm
Monoclonal antibody
Dissolution
Focused beam reflectance measurement
Cho
Biotechnology
Chinese Hamster Ovary
tapped density
bulk density
Cell culture media
Solvent accessible surface area
FTIR
Fourier transformed infrared spectroscopy
parts per million
Ultra High Performance Liquid Chromatography
Granules
Bioengineering
Catalysis
Chemical Engineering (General)
Chemical Health and Safety
Colloid and Surface Chemistry
Filtration and Separation
Fluid Flow and Transfer Processes
Process Chemistry and Technology
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