Article ID Journal Published Year Pages File Type
6741568 Engineering Structures 2013 14 Pages PDF
Abstract
► A model for biochemical, biomechanical and geometrical regulations of bone cells. ► Osteoporosis is affected by ongoing changes in microscopic bone surface availability. ► Surface availability enhances bone loss in the cortex but attenuates it in trabeculae. ► Bone surface availability may accentuate 'trabecularisation' of bone in osteoporosis. ► Biomechanical regulation can stabilise disease progression over long time scales.
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Related Topics
Physical Sciences and Engineering Earth and Planetary Sciences Geotechnical Engineering and Engineering Geology
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The influence of bone surface availability in bone remodelling-A mathematical model including coupled geometrical and biomechanical regulations of bone cells
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