Effect of temperature on the process of preferential solvation of 1,4-dioxane and 12-crown-4 ethers in the mixture of water with formamide

The dissolution enthalpy of 1,4-dioxane and 12-crown-4 ethers in the mixture of water (W) and formamide (F) was measured at four temperatures: 293.15 K, 298.15 K, 303.15 K, 308.15 K. The standard molar enthalpy of solution, ΔsolH°, depends on the size of cyclic ethers and on temperature. The values of ΔsolH° become more negative with increasing molecule size and they increase in magnitude with increasing temperature. The effect of temperature on the process of preferential solvation of cyclic ethers has been discussed.

► The cyclic ethers as a model for study of preferential solvation. ► The 1,4-dioxane and 12-crown-4 ether are preferentially solvated by formamide. ► The enthalpic effect of preferential solvation depends on temperature.