| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 675192 | Thermochimica Acta | 2008 | 5 Pages |
Abstract
The binding of three nucleobase-modified β-CDs, (i.e., mono(6-ade-6-deoxy)-β-CD 2, mono(6-thy-6-deoxy)-β-CD 3, and mono(6-ura-6-deoxy)-β-CD 4) with four bile salts (deoxycholate, DCA; cholate, CA; glycocholate, GCA; and taurocholate, TCA) were investigated by means of circular dichroism, 2D NMR spectroscopy and calorimetric titration. The results show the binding of host 2 with bile salts is weaker and different from hosts 3 and 4. Enthalpy changes between hosts 2-4 and bile salts are much more favorable than those of native β-CD 1, whereas the entropy changes are unfavorable.
Related Topics
Physical Sciences and Engineering
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Fluid Flow and Transfer Processes
Authors
Yu Liu, Qian Zhang, Dong-Sheng Guo, Rui-Jie Zhuang, Li-Hua Wang,