Article ID Journal Published Year Pages File Type
67635 Journal of Molecular Catalysis A: Chemical 2009 5 Pages PDF
Abstract

The chiral diamino-bis(bithiophene) ligands were firstly employed in the iridium(I)-catalyzed asymmetric transfer hydrogenation of aromatic ketones. The new catalyst systems, generated in situ from chiral diamino-bis(bithiophene) ligands and IrCl(CO)(PPh3)2 in iPrOH, gave the corresponding optically active secondary alcohols with high yield and fair to good enantioselectivities (up to 90% ee). The chiral Ir(I)/diamino-bis(bithiophene) complexes were also synthesized and characterized. The XPS spectra showed that the potentially multidentate ligands coordinated to the Ir atom through the nitrogen atoms, while the thiophene pendants did not participate in coordination to the Ir atom.

Graphical abstractThe chiral diamino-bis(bithiophene) ligands were employed in the iridium(I)-catalyzed asymmetric transfer hydrogenation of aromatic ketones firstly, giving the corresponding optically secondary alcohols with high yield and up to 90% ee. The coordination environment of the diamino-thiophene ligands on the Ir atom was also investigated.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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