Ni-nanoparticles: An efficient green catalyst for chemo-selective oxidative coupling of thiols

Use of highly monodispersed, easily recyclable and cheap nickel nanoparticles for oxidative coupling of aliphatic, aromatic, cyclic and heteroaromatic thiols to their corresponding disulfides has been reported. Ni-nanoparticles act as a green catalyst that can selectively catalyse oxidative coupling of thiols to disulfides without producing any over-oxidized products. The catalytic reaction occurred at room temperature with excellent yield under air atmosphere and high TON and TOF value could be achieved. Effect of solvent polarity and size distribution of the Ni-nanoparticles on the catalytic efficiency have been investigated. Nickel nanoparticles could be easily recovered by mild centrifugation.

Graphical abstractA novel method for oxidative coupling of thiols to their corresponding disulfides using Ni-nanoparticles is described. Ni-nanoparticles act as novel and selective catalyst, which efficiently reduces the reaction time, increases the product yield without producing over oxidized products and perform under air atmosphere. Figure optionsDownload full-size imageDownload as PowerPoint slide