Y(NO3)3·6H2O: A novel and reusable catalyst for one pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions

Yttrium(III) nitrate hexahydrate [Y(NO3)3.6H2O] as a catalyst for organic reaction is described for the first time. The catalytic activity is demonstrated using Biginelli reaction as a model under solvent-free conditions. Excellent yields of dihydropyrmidinones are obtained at 70 °C within a short reaction time (10–50 min) and the catalyst is also recyclable. Other advantages over the classical method include greater substrate compatibility, faster reaction rates and easy workup procedures.

Graphical abstractYttrium(III) nitrate hexahydrate [Y(NO3)3.6H2O] as a catalyst for organic reaction is described for the first time. The catalytic activity is demonstrated using Biginelli reaction as a model under solvent-free conditions. Excellent yields of dihydropyrmidinones are obtained at 70 °C within a short reaction time (10–50 min) and the catalyst is also recyclable. Other advantages over the classical method include greater substrate compatibility, faster reaction rates and easy workup procedures.Figure optionsDownload full-size imageDownload as PowerPoint slide