Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6788965 | Comprehensive Psychiatry | 2018 | 5 Pages |
Abstract
Our findings suggest that BD patients have decreased PG volumes, probably due to the long-term hyperactivity of the HPAA and to the consequent strengthening of the negative feedback control towards the PG volume itself. This alteration was particularly evident in females, suggesting a role of gender in affecting PG volumes in BD. Finally, the absence of significant correlations between PG volumes and clinical variables further supports that PG disruption is a trait feature of BD, being independent of symptoms severity and duration of treatment.
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Authors
Giuseppe Delvecchio, Gian Mario Mandolini, Cinzia Perlini, Marco Barillari, Veronica Marinelli, Mirella Ruggeri, A. Carlo Altamura, Marcella Bellani, Paolo Brambilla,