| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 67907 | Journal of Molecular Catalysis A: Chemical | 2007 | 6 Pages |
Tolylphosphines, P(o-tolyl)nPh3 − n have been used in the palladium catalyzed Suzuki cross-coupling reactions of a series of aryl-bromides, chlorides and also two bromoarylphosphine oxides and a bromoarylphosphine with arylboronic acids. The effects of the phosphine, palladium source, base, solvent and promoter salt were investigated. In all studied phosphines, particularly P(o-tolyl)2Ph high conversions and turnovers were seen compared to ortho-unsubstituted phosphines which indicates that other factors such as cyclometallation in addition to steric and electronic effects may be responsible.
Graphical abstractTolylphosphines, P(o-tolyl)nPh3 − n promote efficiently the palladium catalyzed Suzuki cross-coupling reaction of arylboronic acids with aryl halides and bromoarylphosphine oxides with high conversions and turnovers. Figure optionsDownload full-size imageDownload as PowerPoint slide
