Metallophthalocyanines (MPcs) as efficient heterogeneous catalysts for Biginelli condensation: Application and comparison in catalytic activity of different MPcs for one pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones

The catalytic efficiency of various metallophthalocyanines was investigated for three-component condensation reaction of aldehyde, β-dicarbonyl compound and urea to afford corresponding 3,4-dihydropyrimidinones. These phthalocyanine complexes were found to be efficient, recyclable heterogeneous catalyst and showed rate enhancements, high yields and short reaction times in this transformation. Among the various metallophthalocyanines studied, cobalt(II)- phthalocyanine was found to be most active for this transformation.

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